Dendritics公司主要关注人类树突状细胞，希望找到能够促使CD34+造血前体细胞转化为树突状细胞（在GM-CSF和TNF-alpha存在的情况下）的细胞因子。在1992-2005年间，大量的研究使得研究者对人类树突状细胞的产生、细胞通路、C-type凝集素受体的功能及Toll-like受体的活性有了更深的理解。

DENDRITICS was started in 2005 by former members of SCHERING PLOUGH Laboratory for Immunological Research (LIR) in Dardilly, France. From their long experience at LIR, the team members of DENDRITICS have gathered complementary scientific and technological knowledge in different areas of immunology. The initial focus of LIR was in the biology of B lymphocytes, elaboration of human monoclonal antibodies, and in cytokine discovery (IL-3, IL-4, IL-7, IL-10, IL-17, GM-CSF) together with our colleagues of DNAX Research Institute in Palo Alto, California.

Our interest in cytokines led to the finding that human dendritic cells (DCs) could be generated in vitro from CD34+ hematopoietic progenitors cultured in the presence of GM-CSF and TNF-alpha.

The period from 1992 to 2005 saw the specialization of LIR in DC biology and was fuelled by a large-scale effort to discover and study the function of genes specifically expressed by these cells. This program led to a number of findings that contributed in particular to understanding the heterogeneity of DCs, the pathways regulating DC migration, the function of C-type lectin receptors in DCs and the activity of Toll-like receptors in DCs. Many novel genes were discovered through screening of cDNA libraries or through monoclonal antibodies raised against DCs.

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艾美捷科技代理SYnAbs品牌抗体。

SYnAbs公司针对免疫原性较差的化合物和复杂抗原进行开发，其抗体产品线范围包括：针对跨膜蛋白（GPCR、离子通道、转运蛋白）、类固醇、小分子、毒素、脂质和

多糖（针对真菌和细菌）的单克隆抗体。为了应对针对半抗原和膜蛋白产生创新单克隆抗体的挑战，SYnAbs公司开发了一整套技术，结合了：

（1）通过专有技术进行创新抗原设计SYnDNA载体、SYnCell同基因细胞系和特殊佐剂；

（2）专有大鼠LOU物种、野生型、敲除型和多种转基因物种（包括 ATX-Gx 转基因小鼠平台）的多物种免疫；

（3）独特的免疫策略打破免疫耐受并触发特定表位；

（4）稀有B细胞群的选择和分离。

部分单克隆抗体：

Rat anti-human CD2 Siplizumab (LO-CD2a/BTI-322)

Mouse anti-human chemokine receptor

Rat anti-Valproic acid hapten,Rat anti-galactomannan

IgG2b kappa rat anti-His tag (N-ter & C-ter)

IgG1 rat anti-human IgG4

IgG1 kappa rat anti-dinitrophenyl hapten

创新型一抗：

（1）高价值一抗针对复杂和小分子的一抗

（2）同型对照和不相关抗体（抗DNP）

大量二抗：SYnAbs公司为生物技术、制药和体外诊断公司提供大量二抗单克隆抗体目录（超过一百种二抗免疫球蛋白）。

ProSci Incorporated从事抗体等科研试剂的研发、生产和销售。公司现拥有17000多种单、多克隆抗体，产品涵盖了细胞凋亡、信号转导、免疫、肿瘤、细胞生物、神经生物、传染病等领域。公司的抗体大都经免疫亲和层析纯化，具有高纯度、高亲和力、特异性强等特点，所有的ProSci抗体都经过了严格的验证测试和质量控制，已保证高质量的产品。ProSci的抗体广销於世界30多个国家和地区，得到欧美日等生物医学界科研人员和生物制药公司的研发人员的广泛接受。ProSci直销的产品和ProSci的名字已在520多篇科研论文中出现了1500多次，ProSci的经销商和客户都对ProSci产品的质量和服务十分满意。我们的抗体可用于免疫印迹（Western blot) ，免疫组织化学（IHC），免疫细胞化学（ICC），酶联免疫吸附实验（ELISA)和细胞流式分析（FACS)等方面。此外，ProSci还提供标记二抗，重组蛋白，细胞和组织裂解液，细胞涂片，组织切片，多肽等产品与抗体配套使用。ProSci在美国拥有完整的免疫学试剂开发、生产、检测的生产线，包括自己的厂房和实验动物基地，可为您的研究提供信得过的抗体等科研试剂。

ProSci Incorporated is a privately-held biotechnology firm located in San Diego, California. A leader in its field, ProSci’s priority is to provide the highest quality monoclonal, polyclonal, and single domain antibody services in the industry. ProSci’s expertise in antibody production, immunochemistry services, and biological research is realized through customizable services, innovative products, competitive pricing, high-quality research tools, and unparalleled technical support.

ProSci的主要产品包括：

Primary Antibodies

Secondary Antibodies

Recombinant Proteins

Lysates

Antibody Beads

Control Antibodies

Detection Sets

Immunoblots

Peptides

Reagents

Slides

更多详情请联系 

艾美捷科技有限公司

全国服务热线：400-6800-868

邮箱：sales@amyjet.com

网站：www.amyjet.com